Integrative Biological Network Analysis to Identify Shared Genes in Metabolic Disorders.

Identification of common molecular mechanisms in interrelated diseases is essential for better prognoses and targeted therapies. However, complexity of metabolic pathways makes it difficult to discover common disease genes underlying metabolic disorders; and it requires more sophisticated bioinformatics models that combine different types of biological data and computational methods. Accordingly, we built an integrative network analysis model to identify shared disease genes in metabolic syndrome (MS), type 2 diabetes (T2D), and coronary artery disease (CAD). We constructed weighted gene co-expression networks by combining gene expression, protein-protein interaction, and gene ontology data from multiple sources. For 90 different configurations of disease networks, we detected the significant modules by using MCL, SPICi, and Linkcomm graph clustering algorithms.

KT 5720
B9002-.25 250 µg
EUR 483

KT 5720
B9002-.5 500 µg
EUR 818

KT 5823
B6673-.05 50 µg
EUR 123

KT 5823
B6673-.1 100 µg
EUR 190

KT 5823
B6673-.25 250 µg
EUR 361

Plasminogen Receptor (KT) (PLGRKT) Antibody
20-abx318476
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

KT 5823 (PKG kinase inhibitor)
SIH-458-100UG 100 µg
EUR 205
Description: The substance KT 5823 is a pkg kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white solid which is soluble in DMSO (20 mg/ml), dimethyl formamide (20 mg/ml) and ethyl acetate (5 mg/ml).

KT 5823 (PKG kinase inhibitor)
SIH-458-500UG 500 µg
EUR 569
Description: The substance KT 5823 is a pkg kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white solid which is soluble in DMSO (20 mg/ml), dimethyl formamide (20 mg/ml) and ethyl acetate (5 mg/ml).

MAP3K4 antibody
70R-32248 100 ug
EUR 327
Description: Rabbit polyclonal MAP3K4 antibody

Human Arylsulfatase G (ARSG) Antibody
32248-05111 150 ug
EUR 261

Human Arylsulfatase G (ARSG) Antibody (Biotin Conjugate)
32248-05121 150 ug
EUR 369

Human Arylsulfatase G (ARSG) AssayLite Antibody (FITC Conjugate)
32248-05141 150 ug
EUR 428

Human Arylsulfatase G (ARSG) AssayLite Antibody (RPE Conjugate)
32248-05151 150 ug
EUR 428

Human Arylsulfatase G (ARSG) AssayLite Antibody (APC Conjugate)
32248-05161 150 ug
EUR 428

Human Arylsulfatase G (ARSG) AssayLite Antibody (PerCP Conjugate)
32248-05171 150 ug
EUR 471

SDC1 Antibody
32248-100ul 100ul
EUR 252

Rat Chondroitin Sulfate Epitope 3B3(CS3B3 ELISA Kt
GA-E0451RT-48T 48T
EUR 317

Rat Chondroitin Sulfate Epitope 3B3(CS3B3 ELISA Kt
GA-E0451RT-96T 96T
EUR 496

Rat Chondroitin Sulfate Epitope 3B3(CS3B3 ELISA Kt
QY-E11201 96T
EUR 361

Mouse Chondroitin Sulfate Epitope 3B3(CS3B3 ELISA Kt
QY-E20317 96T
EUR 361

Factor XI Antibody Pair
55R-FAC11-KT 5 plates
EUR 745
Description: Factor XI antigen Matched Pair antibody Set for ELISA

Factor IX Antibody Pair
55R-FAC9-KT 5 plates
EUR 760
Description: Factor IX antigen Matched Pair antibody Set for ELISA

Fibrinogen Matched Pair antibody Set
55R-FIBRINO-KT set
EUR 833
Description: Fibrinogen Matched Pair antibody Set for detection of Human Fibrinogen in the research laboratory

Mouse RANKL ELISA Kit
55R-MRANKL-KT 1 kit
EUR 658
Description: ELISA kit for detection of Mouse RANKL in the research laboratory

VWF Antibody Pair
55R-VWF-KT 5 plates
EUR 775
Description: VWF antigen Matched Pair antibody Set for ELISA